gene duplication

Progress in the Study of Gene Duplication

基因重复的研究进展

The study of gene duplication in Charcot-Marie-Tooth disease type 1A patients

Charcot-Marie-Tooth病1A型基因重复诊断研究

Analysis of gene duplication and gene loss in Arabidopsis genome

拟南芥基因倍增及基因流失分析

The preliminary report on the C4 gene duplication in chinese

中国人C4重复基因座位初探

Gene duplication in this superfamily may shed light on this issue .

这个超家族的基因重复研究可能对解决这个问题提供一些启示。

Progress on gene duplication research

基因倍增研究进展

Clinical and electrophysiological study on charcot-Marie-Tooth disease type 1A with gene duplication

基因重复的进行性腓骨肌萎缩症1A型临床与电生理研究

A comprehensive model considering both gene duplication and link dynamics is proposed for protein-protein interaction networks .

提出了一个综合考虑基因复制和边重连机制的蛋白质作用网络模型。

Therefore , transporter gene duplication might promote ramoplanin synthesis .

因此，倍增转运蛋白基因可能会促进雷莫拉宁的合成。

We therefore conclude that alternative splicing and gene duplication may not evolve independently .

因此我们推断，AS和基因复制可能不是独立进化的。

This paper reviews the progress of gene duplication and subsequent functional diversification in the MADS-box gene family .

本文综述了MADS-box基因家族基因重复及其功能分化式样的研究进展。

All these results support the symmetry of the protein tertiary structure is from hypothesis of ancestral gene duplication .

这些数据结果支持了蛋白质结构的对称性是来自于古老基因复制进化的假设。

Advance on Genome and Gene Duplication of Vertebrates

脊椎动物基因组与基因复制研究进展

Our analysis also reveals that continual gene duplication and divergence occurred during the evolution of rodent PRL gene family .

结果还揭示了在啮齿目泌乳刺激素基因家族进化过程中持续不断的发生了基因重复和基因分化事件。

Gene duplication and origin of vertebrates

基因倍增和脊椎动物起源

Gene duplication is universal across all organisms and plays a key role in driving the evolution of genomes and genetic systems .

基因重复是普遍存在的生物学现象，是基因组和遗传系统多样化的重要推动力量，在生物进化过程中发挥着极其重要的作用。

Previous studies suggest that Type ⅱ B topoisomerase evolved from Type ⅱ A by gene duplication , recombination and absence .

先前的研究认为，拓扑异构酶TypeⅡB是由TypeⅡA通过基因的复制、重组和缺失所造成。

Activated NF-kB regulates many kinds of inflammation medium gene duplication after trauma , then causes partial and systemic inflammation reaction .

机体受到创伤后，NF-кB被激活，调节多种炎性介质基因转录，引起局部及全身的炎症反应。

In the study of network modeling of protein-protein interaction networks , gene duplication and link dynamics are regarded as the major mechanisms shaping network structure .

在蛋白质作用网络的建模研究中，基因复制与边的重连过程被认为是塑造网络结构的主要机制。

Interestingly , we found that the loss of alternative splicing in duplicate genes may occur shortly after the gene duplication .

值得注意的是，我们发现复制基因AS形式丢失的过程可能发生在基因复制后很短的时间内。

Conclusion The PCR combined with restriction enzyme digestion represented a relatively sensitive and accurate method for detecting gene duplication in CMT1A cases for clinical diagnosis .

结论PCR双酶切法检测CMT1A基因重复敏感、快速、准确，适于临床推广应用；

MLPA , which is a newly developed method , is a rapid and reliable technique to detect the whole gene duplication of PLP1 .

多重连接依赖的探针扩增这一新方法可用于快速、准确地检测PLP1的全基因重复。

Objective To study the routine methods that can be easily used in clinics to detect the Charcot Marie Tooth ( CMT ) disease gene duplication .

目的探索适合临床应用的检测腓骨肌萎缩症1A型（CMT1A）基因重复的有效方法。

It is evident that many proteins have evolved from gene duplication and fusion into functional oligomers so that they contain repeating structure units with similar functions .

许多的大蛋白就是经过基因序列的内部复制和融合进化而来，这些重复的片断对应着一些相似的结构和功能单元。

During the induction of BIT , some changes happen in the processes of signal triggering and transduction , gene duplication and transcription and protein synthesis and modification in cells .

在BIT的诱导过程中，细胞在信号启动与转导，基因复制与转录，蛋白合成与修饰等环节发生相应的变化。

Motif analyses showed TCS genes ' motif among Arabidopsis , maize and rice have highly homologous , there is a degree of redundancy may reinforce by the gene duplication . 2 .

基序分析表明，水稻各大类基因基序高度保守，但存在着一定程度的冗余现象，这可能是由于基因复制导致的结果。

Biglycan is thought to be the result of a gene duplication . It has a wide distribution in bones , gristles , fibrous tissues and periodontium tissues .

Biglycan是基因扩增的产物，广泛分布在发育的软骨、骨、纤维组织和牙周组织中。

There are multiple molecular mechanisms that can cause genetic disorders such as point mutations , splicing site mutation , insertion / deletion mutations , gene duplication , complex rearrangements and gene copy number abnormalities .

引起遗传性疾病的分子机制有多种，常见的有点突变、小片段插入/缺失突变、拼接位点突变、外显子缺失/重复突变、基因重复和复杂重排及基因拷贝数异常等。

Recently , the whole-genome sequences of many micro-organisms and model species have been completed , resulting in a large amount of data , which makes it feasible to study functional divergence after gene duplication from evolutionary point .

不过近些年来，越来越多的微生物和模式生物的全基因组测序工作已经完成，产生了大量该家族的分子序列数据，这为我们从进化角度分析基因复制后的功能分化提供了一条有效途径。

In this review , we summarized the studies of the molecular mechanisms of gene duplication , the preservation of duplicated gene , the selections acting on duplicated gene , the alternative ways of divergence and the evolution rate .

文章综述了重复基因的产生机制、保留机制、选择作用、分化途径以及重复基因进化速率等方面的相关研究，揭示了基因重复对生物进化的重要性，以引起大家对该领域的关注。